What does COMT do in the brain

Potatoes (all, even sweet potatoes) coffee.Reduces the level of serotonin in the brain.Well, in a nutshell, the comt gene regulates dopamine, a neurotransmitter in the frontal section of your brain.The comt gene codes for the postsynaptic intracellular enzyme comt, which is involved in the methylation and degradation of the catecholamine neurotransmitters dopamine, epinephrine, and.Interestingly, those with this gene appear to experience both negative and positive.

You can see in figure 1 the complex pathway involved in detoxifying stress hormones.This enzyme is critical for brain function, as it is responsible for degrading catecholamines.You can also see that the comt and mao enzymes are major players in the removal of stress hormones and neurotransmitters.Comt is also involved with metabolizing estrogens.These transmitters are crucial for maintaining proper mental function.